Why people with klinefelter syndrome and turner's syndrome are sterile?

Klinefelter syndrome typically causes a boy's testicles to grow at a slower rate than those of other boys. It also prevents the testicles from producing normal amounts of sperm and the hormone testosterone.

Testosterone affects the way a boy develops both physically and sexually. Low hormone levels and problems with sperm production make it difficult or sometimes impossible for a boy with Klinefelter syndrome to father a child later in life.



The turner's syndrome is a rare chromosomal disorder that affects females. The syndrome is caused due to the absence of one of the X chromosomes, making the chromosome composition, 44 + X0, totalling up to 45 chromosomes per diploid cell. Most women with Turner's syndrome are sterile as ovaries are rudimentary, besides other features including delayed or lack of puberty, lack of or poorly developed female secondary sexual characters.