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Question

Write very briefly about Haemophilia

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Solution

  • Haemophilia is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.
  • This results in people bleeding longer after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain.
  • Types of Hemophilia :
  1. Hemophilia A is caused by a mutation in the gene for factor VIII, so there is a deficiency of this clotting factor.
  2. Hemophilia B (also called Christmas disease) results from a deficiency of factor IX due to a mutation in the corresponding gene.
  3. Hemophilia C is a rare genetic disorder caused by missing or defective blot clotting protein called Factor XI.
Treatment is by replacing the missing blood clotting factors.

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